Multi-modal imaging of high-risk ductal carcinoma in situ of the breast using C2Am: a targeted cell death imaging agent

Table 1 Morphological features of MCF10A_DCIS orthotopic xenograft lesions

Cohort	A	B	C
Time of tissue harvest post-implantation (weeks)	2	5	8
Number of fat pads injected (N)	4	6	10
Histologically confirmed DCIS/fat pads examined	2/4	6/6	10/10
Tissue architecture of DCIS lesions
Solid	2/2	4/6	2/6
Cribriform	0/2	3/6	2/6
Comedo	0/2	2/6	6/6
Mixed DCIS (at least two types/specimen)	0/2	4/6	2/6
Associated invasive carcinoma	0/2	2/6	4/6

ISSN: 1465-542X