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Parameters
|
Total
|
BATM-low
|
BATM-high
|
BTSM-low
|
BTSM-high
|
|---|
|
Number of cases (%)
|
Number of cases (%)
|
Number of cases (%)
|
Number of cases (%)
|
Number of cases (%)
|
|---|
|
Age
|
|
≥ 50 years
|
226 (75.8)
|
123 (75.0)
|
41 (25.0)
|
31 (17.2)
|
149 (82.3)
|
|
<50 years
|
72 (24.2)
|
47 (83.9)
|
9 (16.1)
|
11 (16.7)
|
51 (77.3)
|
|
Chi-square p value
| |
0.169
|
0.926
|
|
Molecular subtype
|
|
Luminal A-like
|
166 (55.7)
|
99 (78.0)
|
28 (22.0)
|
37 (26.8)
|
101 (73.2)
|
|
Luminal B-like
|
60 (20.1)
|
39 (79.6)
|
10 (20.4)
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2 (3.8)
|
50 (96.2)
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|
Triple negative
|
38 (12.8)
|
16 (66.7)
|
8 (33.3)
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0 (0.0)
|
30 (100.0)
|
|
HER2 amplified luminal-like
|
24 (8.1)
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11 (78.6)
|
3 (21.4)
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1 (6.3)
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15 (93.7)
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|
HER2 amplified non luminal-like
|
8 (2.7)
|
5 (83.3)
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1 (16.7)
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2 (33.3)
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4 (66.7)
|
|
Chi square p value
| |
0.779
|
0.000011***
|
|
Grading
|
|
G1
|
15 (5)
|
7 (63.6)
|
4 (36.4)
|
4 (30.8)
|
9 (69.2)
|
|
G2
|
103 (34.6)
|
56 (77.8)
|
16 (22.2)
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12 (15.0)
|
68 (85.0)
|
|
G3
|
44 (14.8)
|
25 (78.1)
|
7 (21.9)
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7 (20.6)
|
27 (79.4)
|
|
Chi-square p value
| |
0.594
|
0.337
|
|
Tumor foci
|
|
Unifocal
|
161 (54.0)
|
87 (74.4)
|
30 (25.6)
|
21 (16.0)
|
110 (84.0)
|
|
Multifocal/multicentric
|
137 (46.0)
|
83 (80.6)
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20 (19.4)
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21 (18.9)
|
90 (81.1)
|
|
Chi-square p value
| |
0.272
|
0.554
|
|
Tumor size
|
|
pT1
|
194 (65.1)
|
114 (80.3)
|
28 (19.7)
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31 (20.0)
|
124 (80.0)
|
|
pT2
|
87 (29.2)
|
49 (75.4)
|
16 (24.6)
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8 (11.1)
|
64 (88.9)
|
|
pT3
|
4 (1.3)
|
1 (33.3)
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2 (66.7)
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0 (0.0)
|
3 (100.0)
|
|
pT4
|
13 (4.4)
|
6 (60.0)
|
4 (40.0)
|
3 (25.0)
|
9 (75.0)
|
|
Chi-square p value
| |
0.094
|
0.276
|
|
Axillary lymph node status
|
|
pN0
|
164 (55.0)
|
91 (77.8)
|
26 (22.2)
|
23 (17.6)
|
108 (82.4)
|
|
pN1
|
124 (41.6)
|
73 (76.8)
|
22 (23.2)
|
18 (17.6)
|
84 (82.4)
|
|
pN2
|
4 (1.3)
|
1 (33.3)
|
2 (66.7)
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0 (0.0)
|
4 (100.0)
|
|
Chi-square p value
| |
0.224
|
0.796
|
|
ER status
|
|
Negative
|
57 (19.1)
|
28 (75.7)
|
9 (24.3)
|
4 (8.9)
|
41 (91.1)
|
|
Positive
|
241 (80.9)
|
142 (77.6)
|
41 (22.4)
|
38 (19.3)
|
159 (80.7)
|
|
Chi-square p value
| |
0.799
|
0.096
|
|
PR status
|
|
Negative
|
128 (43.0)
|
67 (75.3)
|
22 (24.7)
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20 (25.0)
|
80 (75.0)
|
|
Positive
|
170 (57.0)
|
103 (78.6)
|
28 (21.4)
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22 (15.5)
|
120 (84.5)
|
|
Chi-square p value
| |
0.561
|
0.362
|
|
HER2 status
|
|
Negative
|
263 (88.3)
|
154 (77.4)
|
45 (22.6)
|
39 (17.8)
|
180 (82.2)
|
|
Positive
|
33 (11.1)
|
16 (76.2)
|
5 (23.8)
|
3 (13.0)
|
20 (87.0)
|
|
Chi-square p value
| |
1.000
|
0.774
|
|
Expression of Ki-67
|
|
≤ 14%
|
167 (56.0)
|
100 (78.1)
|
28 (21.9)
|
37(26.6)
|
102 (73.4)
|
|
>14%
|
60 (20.1)
|
39 (79.6)
|
10 (20.4)
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2(3.8)
|
50 (96.2)
|
|
Chi-square p value
| |
0.832
|
0.001**
|
|
Expression of EP3
|
|
Low (IRS ≤ 1)
|
87 (29.2)
|
43 (68.3)
|
20 (31.7)
|
16 (22.2)
|
56 (77.8)
|
|
High (IRS >1)
|
201 (67.4)
|
124 (80.5)
|
30 (19.5)
|
26 (15.5)
|
142 (84.5)
|
|
Chi-square p value
| |
0.051
|
0.208
|
