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| |
OS%
|
p value
|
HR
|
95% CI
|
DFS%
|
p value
|
HR
|
95% CI
|
|---|
|
A.
|
|
EP3 high+BATM low
|
83.1
| | | |
77.4
| | | |
|
EP3 high+BATM high
|
70.0
|
0.059
|
2.128
|
0.973–4.658
|
66.7
|
0.326
|
1.437
|
0.697–2.962
|
|
EP3 low+BATM low
|
58.1
|
0.01*
|
1.511
|
1.102–2.070
|
60.5
|
0.028*
|
1.405
|
1.037–1.902
|
|
EP3 low+BATM high
|
35.0
|
0.000002*
|
1.756
|
1.391–2.217
|
60.0
|
0.000005*
|
1.922
|
1.453–2.544
|
|
B.
|
|
BATM high+EP3 high
|
70.0
| | | |
66.7
| | | |
|
BATM high+EP3 low
|
35.0
|
0.023*
|
1.647
|
1.070–2.536
|
60.0
|
0.004*
|
2.107
|
1.264–3.513
|
|
C.
|
|
BATM low+EP3 high
|
83.1
| | | |
77.4
| | | |
|
BATM low+EP3 low
|
58.1
|
0.01*
|
1.511
|
1.102–2.070
|
60.5
|
0.028*
|
1.405
|
1.037–1.902
|
|
D.
|
|
EP3 high+BATM low
|
83.1
| | | |
77.4
| | | |
|
EP3 high+BATM high
|
70.0
|
0.059
|
2.128
|
0.973–4.658
|
66.7
|
0.326
|
1.437
|
0.697–2.962
|
|
E.
|
|
EP3 low+BATM low
|
58.1
| | | |
60.5
| | | |
|
EP3 low+BATM high
|
35.0
|
0.007*
|
2.722
|
1.321–5.609
|
60.0
|
0.002*
|
4.049
|
1.665–9.847
|
- BATMs breast adipose tissue macrophage, EP3 prostaglandin E receptor 3, OS overall survival, DFS disease-free survival, p p value, HR hazard ratio, CI confidence interval; *significant (p value < 0.05)